Turkish Journal of
Endocrinology and Metabolism
Case Report

Circulating Antibodies to T4 Causing Discordant Tests of Thyroid Function: A Case Report


Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey


The University of Chicago, Department of Medicine and Pediatrics and the Committee on Genetics, Chicago, USA

Turk J Endocrinol Metab 2014; 18: 19-22
DOI: 10.4274/tjem.2290
Read: 250 Downloads: 84 Published: 01 March 2014


The presence of elevated free thyroxine (fT4) hormone level with non-suppressed thyroid-stimulating hormone (TSH) level is called as “inappropriate secretion of TSH’’. TSH-secreting adenoma, resistance to thyroid hormone (RTH), iodothyronine deiodinase defect or false elevation of measured free serum T4 as in familial dysalbuminemic hyperthyroxinemia (FDH) and the presence of autoantibodies to T4 may be the cause of this entity. We report a case that presented with high serum fT4 and TSH levels associated with autoantibodies to T4.


ISSN 1301-2193 EISSN 1308-9846