Endocrinology Research and Practice
Original Article

Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol

1.

Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

2.

Erciyes University Faculty of Medicine, Department of Biochemistry, Kayseri, Turkey

3.

Erciyes University Faculty of Medicine, Department of Biostatistics, Kayseri, Turkey

Endocrinol Res Pract 2014; 18: 111-115
DOI: 10.4274/tjem.2556
Read: 2027 Downloads: 521 Published: 01 December 2014

ABSTRACT

Purpose: The aim of the study was to compare electrochemiluminescence (ECL) and enzyme immunoassay (EI) methods for the measurement of salivary cortisol (SC).
Material and Method: SC levels in 20 healthy subjects were measured by two different methods (EI and ECL).
Results: The results obtained from EI and ECL methods were found to be significantly correlated.
Discussion: Measuring SC by ECL method is faster and easier than EI in routine practice. Therefore, SC measured by ECL rather than EI may be used as a marker of hypothalamic-pituitary-adrenal (HPA) axis function.

 

 

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