Turkish Journal of
Endocrinology and Metabolism
Original Article

Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol

1.

Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

2.

Erciyes University Faculty of Medicine, Department of Biochemistry, Kayseri, Turkey

3.

Erciyes University Faculty of Medicine, Department of Biostatistics, Kayseri, Turkey

Turk J Endocrinol Metab 2014; 18: 111-115
DOI: 10.4274/tjem.2556
Read: 197 Downloads: 74 Published: 01 December 2014

ABSTRACT

Purpose: The aim of the study was to compare electrochemiluminescence (ECL) and enzyme immunoassay (EI) methods for the measurement of salivary cortisol (SC).
Material and Method: SC levels in 20 healthy subjects were measured by two different methods (EI and ECL).
Results: The results obtained from EI and ECL methods were found to be significantly correlated.
Discussion: Measuring SC by ECL method is faster and easier than EI in routine practice. Therefore, SC measured by ECL rather than EI may be used as a marker of hypothalamic-pituitary-adrenal (HPA) axis function.

 

 

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TURKISH
ISSN 1301-2193 EISSN 1308-9846