Endocrinology Research and Practice
Review Article

Insulin Analogs Applied with Continuous Subcutaneous Insulin Infusion (Pump) in the Treatment of Diabetes

1.

Uludağ University Faculty of Medicine, Department of Endocrinology and Metabolism, Bursa, Turkey

2.

Şevket Yılmaz Training and Research Hospital, Clinic of Endocrinology and Metabolism, Bursa, Turkey

Endocrinol Res Pract 2015; 19: 19-24
DOI: 10.4274/tjem.2635
Read: 1839 Downloads: 532 Published: 01 March 2015

ABSTRACT

Diabetes mellitus (DM) is an important health problem that should be treated efficiently because of its high prevalence and high morbidity and mortality due to its complications. In patients with DM, the application of a treatment which provides physiologic insulin secretion as such in healthy individuals is directly related with the prevention of diabetes complications. Insulin analogs, which were developed in recent years and shown to have pharmacokinetic and pharmacodynamic superiority to human insulin, have made it possible to obtain natural insulin pattern in the body. In addition to development of insulin analogs, introduction of insulin application method of “continuous subcutaneous insulin infusion” (insulin pump) has led a new era in the treatment of DM. In this review, treatment of type 1 and 2 DM patients with insulin analogs, particularly insulin aspart, applied with insulin pump was discussed in the light of the current literature.

 

 

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