Therapeutic Plasmapheresis in Amiodarone-Induced Thyrotoxicosis Resistant to Medical Therapy

ABSTRACT

Amiodarone treatment is associated with thyroid dysfunction resulting in life-threatening thyrotoxicosis. Thyroidectomy may be required if medication is contraindicated or thyroid dysfunction is resistant to the treatment. Therapeutic plasmapheresis (TP) may thus be considered to ensure perioperative euthyroidism, prevent thyroid storm and decrease the risk in surgery. In this case report, we discussed the potential option of TP treatment in the surgical preparation of a patient with Type 1 amiodarone-induced thyrotoxicosis resistant to antithyroid therapy.