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ABSTRACT
High-sensitivity C-reactive protein is a well-known risk factor for cardiovascular heart diseases. In this study we aimed to determine the levels of serum high-sensitivity Creactive protein in patients with newly diagnosed type diabetes mellitus and impaired fasting glucose, and to obtain clinical results by comparing impaired fasting glucose group with type 2 diabetes mellitus and normal groups. Age, sex and body mass index matched 30 normal subjects, 30 patients with impaired fasting glucose, and 30 patients with diabetes were included in the study. We measured levels of serum highsensitivity C-reactive protein in all groups. Subjects with impaired fasting glucose had significantly lower hs-CRP levels than patients with type 2 diabetes mellitus [0.2 (0.04-1.6), 0.48 (0.07-3.12) mg/dl, respectively, p<0.05]. Normal subjects had significantly lower hs-CRP levels than subjects with impaired fasting glucose (p<0.05). The levels of serum high-sensitivity C-reactive protein were correlated to fasting glucose in type 2 diabetes mellitus and impaired fasting glucose groups (p<0.05). Our data suggest that subjects with impaired fasting glucose pose a cardiovascular risk, althogh this was low patients with diabetes.
High-sensitivity C-reactive protein is a well-known risk factor for cardiovascular heart diseases. In this study we aimed to determine the levels of serum high-sensitivity Creactive protein in patients with newly diagnosed type diabetes mellitus and impaired fasting glucose, and to obtain clinical results by comparing impaired fasting glucose group with type 2 diabetes mellitus and normal groups. Age, sex and body mass index matched 30 normal subjects, 30 patients with impaired fasting glucose, and 30 patients with diabetes were included in the study. We measured levels of serum highsensitivity C-reactive protein in all groups. Subjects with impaired fasting glucose had significantly lower hs-CRP levels than patients with type 2 diabetes mellitus [0.2 (0.04-1.6), 0.48 (0.07-3.12) mg/dl, respectively, p<0.05]. Normal subjects had significantly lower hs-CRP levels than subjects with impaired fasting glucose (p<0.05). The levels of serum high-sensitivity C-reactive protein were correlated to fasting glucose in type 2 diabetes mellitus and impaired fasting glucose groups (p<0.05). Our data suggest that subjects with impaired fasting glucose pose a cardiovascular risk, althogh this was low patients with diabetes.