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ABSTRACT
Vascular complications in the patients with diabetes are in the form of micro angiopathy (Micro-vascular, MIV) and macroanglopathy (Macrovascular, Atherosclerosis, MAV). The atherosclerosis of coronary, cerebral and sub-extremity arteria is the major cause for the death of these patients. MIV angiopathy is peculiar to diabetes and occurs as a result of chronic hyperglycemia. MAV is not peculiar to diabetes but it develops earlier, faster, and more widespread in the patients with diabetes (1-4). In our study we examined the arteria carotis communis (ACC) wall thlckness, (Intima-medial complex thickness, IMCT) diameter (D) and the atherosclerotic changes in the carotis bifurcation in the patients with diabetes by using doppler-echocardlography. 42 patients of Type II diabetes and a control group of 15 healthy people were included in the study. The patients who had case histories of cerebrovascular illnesses, non ketotic diabetic coma and the patients who used insulin were excluded from the study. The groups were compared in terms of age, gender, period of diabetes, arterial blood pressure, smoking habits, lipid profile and HbA1c. 17 patients (Group l) were detected to have the complications (500 mg/day and above proteinuria, background retinopathy, sensorial neuropathy, and diabetic foot) but there was no complication in 25 patients (Group II). We also detected the ratio of ACC IMCT, diameter and IMCT/D in the patients of Group l (0.84 ± 0.10 mm, 8.41±0.75 mm, 0.10±0.01) to be meaningfully higher (p<0.01, p<0.05, and 0<0.05) than the patients of Group II (0.74±± 0.05 mm, 7.63±0.33 mm, 0.0910.01) and the ones in the healthy control group (0.73± 0.04 mm, 7.54±0.13 mm, 0.08±0.01). The atherosclerotic plate İncidence in the carotis bifurcation was found to be more severe and more frequent than the other two groups. As a result, we concluded that there was a correlation between the MIV complications and the early atherosclerosis in diabetes.
Vascular complications in the patients with diabetes are in the form of micro angiopathy (Micro-vascular, MIV) and macroanglopathy (Macrovascular, Atherosclerosis, MAV). The atherosclerosis of coronary, cerebral and sub-extremity arteria is the major cause for the death of these patients. MIV angiopathy is peculiar to diabetes and occurs as a result of chronic hyperglycemia. MAV is not peculiar to diabetes but it develops earlier, faster, and more widespread in the patients with diabetes (1-4). In our study we examined the arteria carotis communis (ACC) wall thlckness, (Intima-medial complex thickness, IMCT) diameter (D) and the atherosclerotic changes in the carotis bifurcation in the patients with diabetes by using doppler-echocardlography. 42 patients of Type II diabetes and a control group of 15 healthy people were included in the study. The patients who had case histories of cerebrovascular illnesses, non ketotic diabetic coma and the patients who used insulin were excluded from the study. The groups were compared in terms of age, gender, period of diabetes, arterial blood pressure, smoking habits, lipid profile and HbA1c. 17 patients (Group l) were detected to have the complications (500 mg/day and above proteinuria, background retinopathy, sensorial neuropathy, and diabetic foot) but there was no complication in 25 patients (Group II). We also detected the ratio of ACC IMCT, diameter and IMCT/D in the patients of Group l (0.84 ± 0.10 mm, 8.41±0.75 mm, 0.10±0.01) to be meaningfully higher (p<0.01, p<0.05, and 0<0.05) than the patients of Group II (0.74±± 0.05 mm, 7.63±0.33 mm, 0.0910.01) and the ones in the healthy control group (0.73± 0.04 mm, 7.54±0.13 mm, 0.08±0.01). The atherosclerotic plate İncidence in the carotis bifurcation was found to be more severe and more frequent than the other two groups. As a result, we concluded that there was a correlation between the MIV complications and the early atherosclerosis in diabetes.