Thrombotic Microangiopathy After Spontaneous Pheochromocytoma Rupture: A Rare MEN 2A Case

ABSTRACT

Pheochromocytoma is an adrenal medulla-derived tumor originating from the chromaffin cells that produce and secrete catecholamines. These tumors usually occur sporadically, but they may also be associated with genetic diseases, such as multiple endocrine neoplasia syndrome type 2 (MEN 2). A hypertensive crisis that occurs after the spontaneous rupture of pheochromocytoma, is a rare clinical complication with a high mortality rate. In this article, we present a male case who developed hypertensive crisis and thrombotic microangiopathy (TMA) after a spontaneous pheochromocytoma rupture due to MEN 2A.